Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 6/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 3/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24966370 | 0.87 | PDPK1 (0.64) | PDPK1NTRK1GSK3BJAK3PAK4 | |
| SCHEMBL24966374 | 0.86 | NTRK1 (0.63) | PDPK1NTRK1JAK3MAPTPAK4 | |
| SCHEMBL3751525 | 0.84 | PDGFRB (0.62) | PDPK1NTRK1GSK3BPDGFRBJAK3 | |
| SCHEMBL3751522 | 0.84 | PDGFRB (0.62) | PDPK1NTRK1GSK3BPDGFRBJAK3 | |
| SCHEMBL30155056 | 0.83 | PDPK1 (0.67) | PDPK1NTRK1GSK3BPDGFRBJAK3 | |
| SCHEMBL23369165 | 0.80 | PDPK1 (0.71) | PDPK1NTRK1GSK3BJAK3MAPT | |
| SCHEMBL17674461 | 0.72 | PDPK1 (1.00) | PDPK1NTRK1JAK3MAPTPAK4 | |
| SCHEMBL17679291 | 0.72 | PDPK1 (1.00) | PDPK1NTRK1JAK3MAPTPAK4 | |
| SCHEMBL23369102 | 0.72 | PDPK1 (1.00) | PDPK1NTRK1JAK3MAPTPAK4 | |
| SCHEMBL5999571 | 0.72 | PDPK1 (0.65) | PDPK1NTRK1PDGFRBPAK4RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001942-A1 | 14-3-3 PROTEIN MODULATORS AS ANTITUMOR AGENTS | RAPPOSELLI SIMONA (IT) | 2023-01-26 | — | — | WO | disclosed |