SCHEMBL2496779

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2497165	0.92	MAPT (0.52)	MAPTMAOBKMT2ANPSR1SMN1; SMN2
	SCHEMBL2493689	0.91	MAPT (0.49)	MAPTMAOBKMT2AGAANPSR1
	SCHEMBL13331742	0.90	KMT2A (0.52)	MAPTMAOBKMT2AGAANPSR1
	SCHEMBL2497323	0.90	MAPT (0.49)	MAPTMAOBKMT2AGAANPSR1
	SCHEMBL14847727	0.89	GAA (0.44)	MAPTKMT2AGAANPSR1SMN1; SMN2
	SCHEMBL2496402	0.89	MAPT (0.48)	MAPTMAOBKMT2AGAANPSR1
	SCHEMBL2496404	0.88	MAPT (0.48)	MAPTMAOBKMT2AGAANPSR1
	SCHEMBL2497839	0.87	MAPT (0.44)	MAPTMAOBKMT2AGAANPSR1
	SCHEMBL2472264	0.84	TP53 (0.58)	MAPTKMT2ANPSR1SMN1; SMN2NPC1
	SCHEMBL14837366	0.84	MAPT (0.52)	MAPTMAOBKMT2AGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.