Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 18/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24967972 | 1.00 | TIPARP (0.40) | TIPARPMGLLPARP1 | |
| SCHEMBL24968223 | 0.91 | TIPARP (0.42) | TIPARPPARP1 | |
| SCHEMBL24968907 | 0.91 | TIPARP (0.42) | TIPARP | |
| SCHEMBL24968304 | 0.91 | TIPARP (0.42) | TIPARP | |
| SCHEMBL24968175 | 0.91 | TIPARP (0.49) | TIPARPPARP1 | |
| SCHEMBL24968176 | 0.91 | TIPARP (0.49) | TIPARPPARP1 | |
| SCHEMBL24968224 | 0.91 | TIPARP (0.42) | TIPARPPARP1 | |
| SCHEMBL24967937 | 0.91 | TIPARP (0.49) | TIPARPPARP1 | |
| SCHEMBL24968209 | 0.90 | TIPARP (0.46) | TIPARP | |
| SCHEMBL24968876 | 0.90 | TIPARP (0.46) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4378938-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2024-06-05 | — | — | EP | disclosed |
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |