Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 19/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968182 | 0.87 | TIPARP (0.55) | TIPARP | |
| SCHEMBL24967929 | 0.87 | TIPARP (0.55) | TIPARP | |
| SCHEMBL24967927 | 0.87 | TIPARP (0.55) | TIPARP | |
| SCHEMBL24968362 | 0.85 | TIPARP (0.60) | TIPARP | |
| SCHEMBL24968361 | 0.85 | TIPARP (0.60) | TIPARP | |
| SCHEMBL24968363 | 0.85 | TIPARP (0.60) | TIPARP | |
| SCHEMBL27233794 | 0.84 | TIPARP (0.60) | TIPARPPARP1PARP14PARP12TNKS2 | |
| SCHEMBL27233793 | 0.84 | TIPARP (0.60) | TIPARPPARP1PARP14PARP12TNKS2 | |
| SCHEMBL24968370 | 0.84 | TIPARP (0.60) | TIPARPPARP1PARP14PARP12TNKS2 | |
| SCHEMBL29165900 | 0.77 | TIPARP (0.44) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |