Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.75 |
| ▸ | ERBB2 | P04626 | 14/20 | 0.75 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.75 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL691623 | 0.89 | EGFR (0.82) | EGFRERBB2ERBB4 | |
| SCHEMBL24969094 | 0.89 | EGFR (0.61) | EGFRERBB2ERBB4 | |
| SCHEMBL24968811 | 0.87 | EGFR (0.59) | EGFRERBB2ERBB4 | |
| Allitinib SCHEMBL233985 | 0.87 | EGFR (1.00) | EGFRERBB2ERBB4HDAC3HDAC4 | |
| SCHEMBL12257660 | 0.87 | EGFR (0.60) | EGFRERBB2ERBB4HDAC3HDAC4 | |
| Allitinib SCHEMBL29354831 | 0.87 | EGFR (1.00) | EGFRERBB2ERBB4HDAC3HDAC4 | |
| Allitinib SCHEMBL31732812 | 0.87 | EGFR (1.00) | EGFRERBB2ERBB4HDAC3HDAC4 | |
| SCHEMBL18788863 | 0.86 | EGFR (0.61) | EGFRERBB2ERBB4HDAC3HDAC4 | |
| Allitinib SCHEMBL1402417 | 0.86 | EGFR (0.98) | EGFRERBB2ERBB4HDAC3HDAC4 | |
| SCHEMBL24969077 | 0.86 | EGFR (0.58) | EGFRERBB2ERBB4HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |