Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 18/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968404 | 1.00 | TIPARP (0.46) | TIPARPHRH3MEN1KMT2A | |
| SCHEMBL24968432 | 1.00 | TIPARP (0.46) | TIPARPHRH3MEN1KMT2A | |
| SCHEMBL27233724 | 1.00 | TIPARP (0.46) | TIPARPHRH3MEN1KMT2A | |
| SCHEMBL24968402 | 1.00 | TIPARP (0.46) | TIPARPHRH3MEN1KMT2A | |
| SCHEMBL27233754 | 0.87 | TIPARP (0.53) | TIPARP | |
| SCHEMBL24968386 | 0.87 | TIPARP (0.53) | TIPARP | |
| SCHEMBL24968877 | 0.87 | TIPARP (0.53) | TIPARP | |
| SCHEMBL24968894 | 0.86 | TIPARP (0.47) | TIPARPMEN1KMT2A | |
| SCHEMBL24968339 | 0.86 | TIPARP (0.54) | TIPARP | |
| SCHEMBL24968935 | 0.86 | TIPARP (0.54) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |