Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.60 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152232 | 1.00 | MAOB (0.60) | MAOBMRGPRX4IDO1ALDH1A1GAA | |
| SCHEMBL30013585 | 0.83 | MAOB (0.57) | MAOBMRGPRX4IDO1ALDH1A1KDM4E | |
| SCHEMBL4416180 | 0.83 | MAOB (0.57) | MAOBMRGPRX4IDO1ALDH1A1KDM4E | |
| SCHEMBL8807037 | 0.81 | MAOB (0.60) | MAOBALDH1A1GAAL3MBTL1KDM4E | |
| SCHEMBL2749493 | 0.81 | MRGPRX4 (0.81) | MAOBMRGPRX4IDO1 | |
| SCHEMBL2332329 | 0.80 | MRGPRX4 (0.56) | MAOBMRGPRX4SLC6A4 | |
| SCHEMBL22937898 | 0.78 | MRGPRX4 (0.71) | MAOBMRGPRX4 | |
| SCHEMBL23592034 | 0.78 | MRGPRX4 (0.63) | MAOBMRGPRX4ALDH1A1GAAL3MBTL1 | |
| SCHEMBL29824921 | 0.78 | MRGPRX4 (0.63) | MAOBMRGPRX4ALDH1A1GAAL3MBTL1 | |
| SCHEMBL23579297 | 0.78 | MRGPRX4 (0.47) | MAOBMRGPRX4ALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |