Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 5/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP10 | P09238 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.39 |
| ▸ | POLR1A | O95602 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31143013 | 1.00 | POLB (0.43) | POLBBACE1SSTR4NAMPTANO1 | |
| SCHEMBL24969919 | 0.86 | MEN1 (0.44) | POLBBACE1SSTR4NAMPTANO1 | |
| SCHEMBL31143020 | 0.86 | MEN1 (0.44) | POLBBACE1SSTR4NAMPTANO1 | |
| SCHEMBL8253734 | 0.80 | HDAC3 (0.52) | BACE1SSTR4NAMPTPDE10AUSP30 | |
| SCHEMBL2593585 | 0.79 | PDE10A (0.48) | POLBBACE1NAMPTPDE10AKCNK3 | |
| SCHEMBL24969922 | 0.75 | USP30 (0.40) | BACE1SSTR4NAMPTUSP30RORC | |
| SCHEMBL31143006 | 0.75 | USP30 (0.40) | BACE1SSTR4NAMPTUSP30RORC | |
| SCHEMBL29864697 | 0.74 | SSTR4 (0.41) | POLBSSTR4NAMPTANO1USP30 | |
| SCHEMBL22702770 | 0.74 | SSTR4 (0.41) | POLBSSTR4NAMPTANO1USP30 | |
| SCHEMBL31143019 | 0.74 | HTR3B (0.57) | POLBBACE1NAMPTPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002011-A1 | GRAM-NEGATIVE BACTERIA EFFLUX PUMP INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-01-26 | — | — | WO | disclosed |