Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | FPR2 | P25090 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.59 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.59 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.59 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583404 | 0.95 | SMN1; SMN2 (0.75) | SMN1; SMN2GLAKMT2ATAAR1ALDH1A1 | |
| SCHEMBL3656068 | 0.84 | SMN1; SMN2 (0.65) | SMN1; SMN2GLAKMT2ATAAR1ALDH1A1 | |
| SCHEMBL30858767 | 0.83 | SMN1; SMN2 (0.77) | SMN1; SMN2GLAKMT2ATAAR1ALDH1A1 | |
| SCHEMBL17919369 | 0.83 | SMN1; SMN2 (0.77) | SMN1; SMN2GLAKMT2ATAAR1ALDH1A1 | |
| SCHEMBL10516281 | 0.82 | SMN1; SMN2 (0.71) | SMN1; SMN2GLAKMT2ATAAR1ALDH1A1 | |
| SCHEMBL4322629 | 0.81 | GLA (0.77) | SMN1; SMN2GLAKMT2ATAAR1ALDH1A1 | |
| SCHEMBL659053 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2GLAKMT2ATAAR1ALDH1A1 | |
| SCHEMBL12773610 | 0.81 | SMN1; SMN2 (0.75) | SMN1; SMN2GLAKMT2ATAAR1ALDH1A1 | |
| SCHEMBL5944191 | 0.81 | SMN1; SMN2 (0.75) | SMN1; SMN2GLAKMT2ATAAR1ALDH1A1 | |
| SCHEMBL1728418 | 0.81 | CNR1 (0.59) | KMT2AGAAPLAAT5PLAAT4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097410-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2010-09-02 | — | — | WO | disclosed |