⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754178 | 1.00 | — | — | |
| SCHEMBL25754182 | 1.00 | — | — | |
| SCHEMBL24973031 | 1.00 | — | — | |
| SCHEMBL22598548 | 0.88 | KDM4E (0.33) | — | |
| SCHEMBL22618373 | 0.88 | KDM4E (0.33) | — | |
| SCHEMBL22327256 | 0.88 | KDM4E (0.33) | — | |
| SCHEMBL22327323 | 0.88 | KDM4E (0.33) | — | |
| SCHEMBL24973040 | 0.88 | — | — | |
| SCHEMBL24973030 | 0.88 | — | — | |
| SCHEMBL25754186 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-06-29 | — | — | US | disclosed |
| US-20230028359-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-01-26 | — | — | US | disclosed |