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Sugi Predict / Compounds / SCHEMBL24973759

SCHEMBL24973759

SCHEMBL24973759

C1=Cc2c(cccc2-c2ccc(-c3ccc(-c4ccc(-c5nc(-c6ccccc6)nc(-c6cccc7oc8ccccc8c67)n5)cc4)c4ccccc34)c3c2oc2ccccc23)CC1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.36
▸ MAPT P10636 4/20 0.34
▸ KDM4E B2RXH2 3/20 0.34
▸ LMNA P02545 2/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ ALDH1A1 P00352 3/20 0.32
▸ POLB P06746 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ CDC14B O60729 1/20 0.31
▸ CDC14A Q9UNH5 1/20 0.31
▸ BACE1 P56817 1/20 0.30
▸ HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24972430 0.90 TSHR (0.33) TSHRMAPTKDM4ELMNAMAPK1
SCHEMBL24315258 0.89 BACE1 (0.33) BACE1
SCHEMBL26289413 0.87 TSHR (0.33) TSHRMAPTKDM4ELMNAMAPK1
SCHEMBL23816400 0.85 TSHR (0.35) TSHRMAPTKDM4ELMNAMAPK1
SCHEMBL23816398 0.84 TSHR (0.34) TSHRMAPTKDM4ELMNAMAPK1
SCHEMBL23821720 0.84 TSHR (0.31) TSHR
SCHEMBL23820366 0.84 MAPT (0.40) TSHRMAPTKDM4ELMNAMAPK1
SCHEMBL23816409 0.84 MAPT (0.42) TSHRMAPTKDM4ELMNAMAPK1
SCHEMBL25651480 0.84 TSHR (0.35) TSHRMAPTKDM4ELMNAMAPK1
SCHEMBL25677831 0.84 TSHR (0.35) TSHRMAPTKDM4ELMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023002447-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 — — WO disclosed