SCHEMBL24975375 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	SCN10A	Q9Y5Y9	1/20	0.46

▸	TRPV1	Q8NER1	12/20	0.42

▸	TLR7	Q9NYK1	1/20	0.42

▸	MAPK1	P28482	4/20	0.39

▸	HSD17B10	Q99714	3/20	0.39

▸	KDM4E	B2RXH2	2/20	0.39

▸	ALDH1A1	P00352	2/20	0.39

▸	MAPT	P10636	1/20	0.39

▸	TSHR	P16473	1/20	0.39

▸	CASP1	P29466	1/20	0.39

▸	CASP7	P55210	1/20	0.39

▸	GFER	P55789	1/20	0.39

▸	TDP1	Q9NUW8	1/20	0.39

▸	TP53	P04637	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22193267	0.79	TRPV1 (0.43)	SCN10ATRPV1TLR7MAPK1HSD17B10
SCHEMBL5813387	0.79	TRPV1 (0.47)	TRPV1
SCHEMBL27965536	0.79	TRPV1 (0.41)	SCN10ATRPV1TLR7
SCHEMBL2527414	0.78	SCN10A (0.45)	SCN10ATRPV1TLR7MAPK1HSD17B10
SCHEMBL12167278	0.78	NPSR1 (0.43)	SCN10ATRPV1TLR7MAPK1HSD17B10
SCHEMBL3091430	0.78	SCN10A (0.42)	SCN10ATRPV1TLR7MAPK1HSD17B10
SCHEMBL13724961	0.78	NPSR1 (0.43)	SCN10ATRPV1TLR7MAPK1HSD17B10
SCHEMBL1474393	0.78	SCN10A (0.53)	SCN10ATRPV1TLR7
SCHEMBL4088039	0.76	SCN10A (0.55)	SCN10ATRPV1TLR7MAPK1HSD17B10
SCHEMBL1473835	0.76	TRPV1 (0.47)	SCN10ATRPV1TLR7MAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023005894-A1	INHIBITOR COMPOUND FOR WNT PATHWAY	杭州阿诺生物医药科技有限公司	2023-02-02	—	—	WO	disclosed