Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.38 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | LIPC | P11150 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428970 | 1.00 | ABCG2 (0.43) | ABCG2ABCB1GABRA1GABRG2GABRB3 | |
| SCHEMBL24975467 | 0.94 | ABCG2 (0.45) | ABCG2ABCB1GABRA1GABRG2GABRB3 | |
| SCHEMBL31428594 | 0.94 | ABCG2 (0.45) | ABCG2ABCB1GABRA1GABRG2GABRB3 | |
| SCHEMBL31428862 | 0.88 | ABCG2 (0.41) | ABCG2ABCB1GABRA1GABRG2GABRB3 | |
| SCHEMBL24975497 | 0.88 | ABCG2 (0.41) | ABCG2ABCB1GABRA1GABRG2GABRB3 | |
| SCHEMBL24977054 | 0.88 | ABCG2 (0.47) | ABCG2ABCB1GABRA1GABRG2GABRB3 | |
| SCHEMBL31428706 | 0.88 | ABCG2 (0.47) | ABCG2ABCB1GABRA1GABRG2GABRB3 | |
| SCHEMBL24976143 | 0.86 | ABCG2 (0.46) | ABCG2ABCB1GABRA1GABRG2GABRB3 | |
| SCHEMBL31428903 | 0.86 | ABCG2 (0.46) | ABCG2ABCB1GABRA1GABRG2GABRB3 | |
| SCHEMBL24975470 | 0.85 | ABCG2 (0.43) | ABCG2ABCB1GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |