Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428793 | 1.00 | KDM4E (0.46) | KDM4EPKMHPGDUSP2ALDH1A1 | |
| SCHEMBL31428482 | 0.89 | HPGD (0.41) | HPGDALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL24975789 | 0.89 | HPGD (0.41) | HPGDALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL31428610 | 0.86 | GRM2 (0.46) | KDM4EPKMHPGDUSP2ALDH1A1 | |
| SCHEMBL31428552 | 0.85 | MEN1 (0.46) | KDM4EPKMHPGDTSHRPDCD1 | |
| SCHEMBL31428537 | 0.83 | PDCD1 (0.52) | KDM4EPKMHPGDUSP2ALDH1A1 | |
| SCHEMBL31428699 | 0.82 | HTR2C (0.53) | KDM4EPKMHPGDUSP2ALDH1A1 | |
| SCHEMBL31428513 | 0.81 | PDCD1 (0.53) | KDM4EPKMHPGDUSP2ALDH1A1 | |
| SCHEMBL24977037 | 0.79 | CNR2 (0.47) | ALDH1A1 | |
| SCHEMBL31428639 | 0.79 | CNR2 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |