Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428815 | 0.82 | HPGD (0.52) | HPGDSMN1; SMN2MYCKDM4EPKM | |
| SCHEMBL31428523 | 0.80 | GRM2 (0.51) | HPGDMYCGRM2KDM4EPKM | |
| SCHEMBL31429082 | 0.80 | HPGD (0.62) | HPGDSMN1; SMN2MYCKDM4EPKM | |
| SCHEMBL31428513 | 0.79 | PDCD1 (0.53) | HPGDGRM2KDM4EPKMALDH1A1 | |
| SCHEMBL31428504 | 0.78 | MAPK1 (0.53) | HPGDSMN1; SMN2MYCKDM4EPKM | |
| SCHEMBL31428834 | 0.77 | GRM2 (0.48) | HPGDSMN1; SMN2MYCGRM2KDM4E | |
| SCHEMBL31428625 | 0.77 | HPGD (0.49) | HPGDSMN1; SMN2MYCKDM4EPKM | |
| SCHEMBL31428537 | 0.77 | PDCD1 (0.52) | HPGDKDM4EPKMALDH1A1CYP1A2 | |
| SCHEMBL31428810 | 0.76 | HPGD (0.48) | HPGDMYCKDM4EPKMALDH1A1 | |
| SCHEMBL31429010 | 0.74 | AR (0.61) | HPGDSMN1; SMN2MYCGRM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |