Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SLC8A1 | P32418 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 3/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15921792 | 0.80 | HPGD (0.60) | HPGDHTR2CL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1657049 | 0.80 | HPGD (0.60) | HPGDHTR2CL3MBTL1SMN1; SMN2OGA | |
| SCHEMBL10039298 | 0.79 | HPGD (0.58) | HPGDHTR2CL3MBTL1SMN1; SMN2OGA | |
| SCHEMBL2060505 | 0.79 | HPGD (0.58) | HPGDHTR2CL3MBTL1SMN1; SMN2OGA | |
| SCHEMBL31206782 | 0.77 | HPGD (0.53) | HPGDHTR2CL3MBTL1SMN1; SMN2OGA | |
| SCHEMBL26702865 | 0.75 | HPGD (0.54) | HPGDHTR2CL3MBTL1SMN1; SMN2OGA | |
| SCHEMBL23213621 | 0.75 | HPGD (0.54) | HPGDHTR2CL3MBTL1SMN1; SMN2OGA | |
| SCHEMBL6221064 | 0.74 | HPGD (0.75) | HPGDL3MBTL1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11387823 | 0.73 | HTR2C (0.67) | HPGDHTR2CL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31428696 | 0.73 | HTR2C (0.48) | HPGDHTR2CL3MBTL1SMN1; SMN2OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | HPGD 4233/4885HTR2C 4858/4885L3MBTL1 1560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.