Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428592 | 1.00 | MEN1 (0.47) | MEN1KMT2ARAB9APKMHTT | |
| SCHEMBL31428809 | 0.82 | TDP1 (0.50) | MEN1KMT2ARAB9APKMHTT | |
| SCHEMBL24977225 | 0.82 | TDP1 (0.50) | MEN1KMT2ARAB9APKMHTT | |
| SCHEMBL24975807 | 0.81 | HTR2C (0.51) | MEN1KMT2ARAB9APKMNPC1 | |
| SCHEMBL31428478 | 0.81 | HTR2C (0.51) | MEN1KMT2ARAB9APKMNPC1 | |
| SCHEMBL31429030 | 0.77 | MAPT (0.42) | MEN1KMT2ARAB9APKMHTT | |
| SCHEMBL16502582 | 0.75 | GRIN2D (0.54) | MEN1KMT2ARAB9APTPN1NPC1 | |
| SCHEMBL24975610 | 0.73 | NPC1 (0.48) | MEN1KMT2ARAB9APKMHTT | |
| SCHEMBL31428836 | 0.73 | NPC1 (0.48) | MEN1KMT2ARAB9APKMHTT | |
| SCHEMBL31357157 | 0.73 | PTPN1 (0.70) | MEN1KMT2ARXFP1PTPN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |