Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | PLAUR | Q03405 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 3/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ROS1 | P08922 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | MARK3 | P27448 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428977 | 1.00 | PDCD1 (0.42) | PDCD1CD274PLAURHPGDMEN1 | |
| SCHEMBL31428962 | 0.94 | PDCD1 (0.42) | PDCD1CD274PLAURHPGDMEN1 | |
| SCHEMBL31428898 | 0.91 | PDCD1 (0.46) | PDCD1CD274PLAURHPGDMEN1 | |
| SCHEMBL31428944 | 0.90 | PDCD1 (0.38) | PDCD1CD274PLAURHPGDRAB9A | |
| SCHEMBL31428945 | 0.89 | PDCD1 (0.47) | PDCD1CD274PLAURHPGDMEN1 | |
| SCHEMBL31428782 | 0.89 | PDCD1 (0.49) | PDCD1CD274PLAURHPGDRAB9A | |
| SCHEMBL31428624 | 0.88 | PDCD1 (0.48) | PDCD1CD274PLAURHPGDMEN1 | |
| SCHEMBL31428666 | 0.86 | PDCD1 (0.48) | PDCD1CD274PLAURHPGDRAB9A | |
| SCHEMBL31428873 | 0.86 | PDCD1 (0.42) | PDCD1CD274PLAURHPGDERN1 | |
| SCHEMBL31428789 | 0.85 | PDCD1 (0.46) | PDCD1CD274PLAURHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |