Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ERN1 | O75460 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428605 | 1.00 | GRM2 (0.48) | GRM2RAB9AERN1HSD17B10MEN1 | |
| SCHEMBL31428711 | 0.91 | GRM2 (0.51) | GRM2ERN1ALDH1A1HPGDHTT | |
| SCHEMBL31428980 | 0.87 | MEN1 (0.47) | GRM2RAB9AHSD17B10MEN1KMT2A | |
| SCHEMBL24975625 | 0.87 | MEN1 (0.47) | GRM2RAB9AHSD17B10MEN1KMT2A | |
| SCHEMBL31428671 | 0.86 | HPGD (0.50) | GRM2ERN1ALDH1A1HPGD | |
| SCHEMBL31428481 | 0.85 | ERN1 (0.52) | GRM2RAB9AERN1MEN1KMT2A | |
| SCHEMBL31428712 | 0.85 | GRM2 (0.49) | GRM2ERN1ALDH1A1HPGD | |
| SCHEMBL24975793 | 0.83 | GRM2 (0.47) | GRM2RAB9AERN1HSD17B10MEN1 | |
| SCHEMBL31428507 | 0.83 | GRM2 (0.47) | GRM2RAB9AERN1HSD17B10MEN1 | |
| SCHEMBL31428784 | 0.83 | MAPT (0.52) | GRM2ERN1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |