SCHEMBL2497801

SCHEMBL2497801

CCCCOc1cc(COc2cccc([C@@H](C)C(C)C(=O)O)c2)ccc1-c1cc(OC)ccc1F

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2496841 1.00 FFAR1 (0.57) FFAR1
SCHEMBL2500878 0.97 FFAR1 (0.57) FFAR1
SCHEMBL2501416 0.97 FFAR1 (0.57) FFAR1
SCHEMBL2501352 0.89 FFAR1 (0.53) FFAR1
SCHEMBL2503945 0.89 FFAR1 (0.53) FFAR1
SCHEMBL2518943 0.88 FFAR1 (0.73) FFAR1
SCHEMBL2495117 0.88 FFAR1 (0.73) FFAR1
SCHEMBL2499805 0.88 FFAR1 (0.46) FFAR1
SCHEMBL2503693 0.88 FFAR1 (0.46) FFAR1
SCHEMBL2494936 0.88 FFAR1 (0.62) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8030354-B2 2-(5,5-Dimethylcyclopent-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; metabolic disorders such as type II diabetes AMGEN INC. (US) 2011-10-04 US disclosed