Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24984639 | 1.00 | POLB (0.35) | POLBCFTRKMT2AMEN1HPGD | |
| SCHEMBL24345458 | 0.92 | POLB (0.37) | POLBCFTRKMT2AMEN1HPGD | |
| SCHEMBL24345299 | 0.91 | POLB (0.36) | POLBCFTRKMT2AMEN1HPGD | |
| SCHEMBL24345459 | 0.91 | POLB (0.39) | POLBCFTRKMT2AMEN1HPGD | |
| SCHEMBL24985386 | 0.91 | POLB (0.36) | POLBCFTRKMT2AMEN1HPGD | |
| SCHEMBL24985387 | 0.91 | POLB (0.36) | POLBCFTRKMT2AMEN1HPGD | |
| SCHEMBL24986217 | 0.90 | POLB (0.35) | POLBCFTRKMT2AMEN1HPGD | |
| SCHEMBL24986216 | 0.90 | POLB (0.35) | POLBCFTRKMT2AMEN1HPGD | |
| SCHEMBL24345270 | 0.89 | POLB (0.38) | POLBCFTRKMT2AMEN1HPGD | |
| SCHEMBL24345669 | 0.89 | POLB (0.38) | POLBCFTRKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230125803-A1 | ANTIVIRAL HETEROCYCLIC COMPOUNDS | ENANTA PHARM INC (US) | 2023-04-27 | — | — | US | disclosed |
| US-11572367-B2 | Antiviral heterocyclic compounds | ENANTA PHARMACEUTICALS, INC. (US) | 2023-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572367-B2 | Antiviral heterocyclic compounds | ACE, HPRT1, ACE2 | POLB 2743/4885CFTR 283/4885KMT2A 2570/4885 |
| US-20230125803-A1 | ANTIVIRAL HETEROCYCLIC COMPOUNDS | ACE, HPRT1, ACE2 | POLB 2743/4885CFTR 283/4885KMT2A 2570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.