SCHEMBL2498885

SCHEMBL2498885

COC(=O)C[C@@H](c1cccc(OCc2ccc(-c3cc(OC)ccc3F)c(CN3CCCC3)c2)c1)C1CC1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2498349 1.00 FFAR1 (0.67) FFAR1
SCHEMBL2497261 0.99 FFAR1 (0.66) FFAR1
SCHEMBL2501922 0.99 FFAR1 (0.66) FFAR1
SCHEMBL2494926 0.93 FFAR1 (0.77) FFAR1
SCHEMBL2498810 0.93 FFAR1 (0.77) FFAR1
SCHEMBL2497730 0.93 FFAR1 (0.76) FFAR1
SCHEMBL2500003 0.93 FFAR1 (0.76) FFAR1
SCHEMBL2497374 0.93 FFAR1 (0.76) FFAR1
SCHEMBL2502013 0.93 FFAR1 (0.76) FFAR1
SCHEMBL2499234 0.91 FFAR1 (0.66) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8030354-B2 2-(5,5-Dimethylcyclopent-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; metabolic disorders such as type II diabetes AMGEN INC. (US) 2011-10-04 US disclosed