Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25014985 | 0.88 | ADORA2A (0.41) | ADORA2AADORA1NPY5RCHEK1KCNH2 | |
| SCHEMBL24988637 | 0.86 | ADORA2A (0.40) | ADORA2AADORA1NPY5RCHEK1KCNH2 | |
| SCHEMBL3008784 | 0.86 | ADORA2A (0.41) | ADORA2AADORA1NPY5RCHEK1KCNH2 | |
| SCHEMBL25014500 | 0.85 | ADORA2A (0.41) | ADORA2AADORA1NPY5RCHEK1KCNH2 | |
| SCHEMBL29205640 | 0.85 | ADORA2A (0.39) | ADORA2AADORA1NPY5RCHEK1KCNH2 | |
| SCHEMBL29205618 | 0.84 | ADORA2A (0.39) | ADORA2AADORA1NPY5RCHEK1KCNH2 | |
| SCHEMBL25014577 | 0.84 | ADORA2A (0.41) | ADORA2AADORA1NPY5RCHEK1KCNH2 | |
| SCHEMBL24988638 | 0.84 | MPL (0.39) | ADORA2AADORA1NPY5RCHEK1KCNH2 | |
| SCHEMBL3008877 | 0.83 | ADORA2A (0.42) | ADORA2AADORA1NPY5RCHEK1KCNH2 | |
| SCHEMBL29205668 | 0.83 | ADORA2A (0.40) | ADORA2AADORA1NPY5RCHEK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023013994-A1 | NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 주식회사 미토이뮨테라퓨틱스 | 2023-02-09 | — | — | WO | disclosed |