SCHEMBL24990967

SCHEMBL24990967

CC(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H]1CCC(=O)NCCNC(=O)CNC(=O)CNC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 1/20 0.48
▸ FCGRT P55899 1/20 0.47
▸ MC4R P32245 12/20 0.45
▸ TUBB4A P04350 2/20 0.45
▸ TUBB P07437 2/20 0.45
▸ TUBA3C P0DPH7 2/20 0.45
▸ TUBA1B P68363 2/20 0.45
▸ TUBA4A P68366 2/20 0.45
▸ TUBB4B P68371 2/20 0.45
▸ TUBB3 Q13509 2/20 0.45
▸ TUBB2A Q13885 2/20 0.45
▸ TUBB8 Q3ZCM7 2/20 0.45
▸ TUBA3E Q6PEY2 2/20 0.45
▸ TUBA1A Q71U36 2/20 0.45
▸ TUBA1C Q9BQE3 2/20 0.45
▸ TUBB6 Q9BUF5 2/20 0.45
▸ TUBB2B Q9BVA1 2/20 0.45
▸ TUBB1 Q9H4B7 2/20 0.45
▸ EPHA2 P29317 1/20 0.45
▸ SIRT2 Q8IXJ6 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24991494 0.98 FURIN (0.51) FURINFCGRTMC4RTUBB4ATUBB
SCHEMBL24989722 0.93 FCGRT (0.48) FURINFCGRTMC4RTUBB4ATUBB
SCHEMBL24991495 0.89 MC4R (0.47) MC4RMC3RMC1RMC5R
SCHEMBL24991159 0.89 MC4R (0.58) MC4RTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL23750196 0.89 MC4R (0.58) MC4RTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL24990966 0.89 MC4R (0.58) MC4RTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL24989725 0.89 MC4R (0.58) MC4RTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL19473850 0.87 FCGRT (0.52) FURINFCGRTMC4RTUBB4ATUBB
SCHEMBL24989701 0.87 MC4R (0.60) FURINMC4RTUBB4ATUBBTUBA3C
SCHEMBL24989720 0.87 MC4R (0.59) FURINMC4RTUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications PALATIN TECHNOLOGIES, INC. (US) 2023-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications MC1R, MC3R, MC5R FURIN 803/4885FCGRT 1295/4885MC4R 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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