Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 5/20 | 0.56 |
| ▸ | PLK1 | P53350 | 2/20 | 0.55 |
| ▸ | ULK1 | O75385 | 3/20 | 0.54 |
| ▸ | EGFR | P00533 | 8/20 | 0.51 |
| ▸ | INSR | P06213 | 2/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24992441 | 0.96 | ALK (0.51) | ALKPLK1ULK1EGFRMET | |
| SCHEMBL24992322 | 0.91 | ALK (0.57) | ALKPLK1ULK1EGFRINSR | |
| SCHEMBL24993233 | 0.91 | ALK (0.50) | ALKEGFRINSRMETIGF1R | |
| SCHEMBL24992280 | 0.90 | EGFR (0.64) | ALKPLK1ULK1EGFRINSR | |
| SCHEMBL24993661 | 0.87 | ALK (0.46) | ALKEGFRINSRMETIGF1R | |
| SCHEMBL24992442 | 0.86 | EGFR (0.51) | ALKPLK1ULK1EGFRMET | |
| SCHEMBL26378998 | 0.85 | ALK (0.56) | ALKPLK1ULK1EGFRINSR | |
| SCHEMBL24993047 | 0.84 | ALK (0.70) | ALKPLK1EGFRINSRMET | |
| SCHEMBL24992448 | 0.83 | EGFR (0.69) | ALKPLK1EGFRMET | |
| SCHEMBL24992286 | 0.82 | EGFR (0.75) | ALKPLK1ULK1EGFRINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |