SCHEMBL24992357

SCHEMBL24992357

CN(C)c1ccc2cc(/C=C3\NC(=S)NC3=O)sc2c1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PRF1 P14222 16/20 0.54
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ CTSB P07858 1/20 0.40
▸ ELANE P08246 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24999651 0.81 PRF1 (0.44) PRF1MEN1KMT2A
SCHEMBL24992630 0.77 PRF1 (0.45) PRF1
SCHEMBL15319819 0.73 MAPT (0.71) PRF1MEN1KMT2ALMNAMAPT
SCHEMBL24991965 0.73 MAPT (0.71) PRF1MEN1KMT2ALMNAMAPT
SCHEMBL21234686 0.72 CYP2A6 (0.53) MEN1KMT2AMAPT
SCHEMBL24992337 0.72 PRF1 (0.56) PRF1
SCHEMBL25000062 0.71 NAT1 (0.44) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL12633690 0.71 PRF1 (1.00) PRF1
SCHEMBL14761960 0.71 PRF1 (1.00) PRF1
SCHEMBL14761955 0.71 PRF1 (1.00) PRF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023011658-A1 METHOD FOR DETECTING AND QUANTIFYING RNA 纳莹(上海)生物科技有限公司 2023-02-09 — — WO disclosed
WO-2023011657-A1 METHOD FOR DETECTING AND QUANTIFYING RNA 纳莹(上海)生物科技有限公司 2023-02-09 — — WO disclosed
Send feedback