Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 20/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.49 |
| ▸ | OXTR | P30559 | 7/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.49 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5678532 | 0.93 | AVPR1B (0.55) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL5675833 | 0.89 | AVPR1B (0.52) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL5674427 | 0.88 | AVPR1B (0.51) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL5675270 | 0.88 | AVPR1B (0.50) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL2493392 | 0.88 | AVPR1B (0.50) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL2495355 | 0.86 | AVPR1B (0.49) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL2498777 | 0.85 | AVPR1B (0.54) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL2495093 | 0.85 | AVPR1B (0.54) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL5674074 | 0.85 | AVPR1B (0.42) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL2497275 | 0.84 | AVPR1B (0.53) | AVPR1BAVPR1AOXTRAVPR2GPR65 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030499-B2 | 1,3-dihydro-2H-indole-2-one compound and pyrrolidine-2-one compound fused with aromatic heterocycle | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-10-04 | — | — | US | disclosed |