⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22661417 | 0.78 | — | — | |
| SCHEMBL23133519 | 0.78 | — | — | |
| SCHEMBL20330461 | 0.78 | PIK3CD (0.31) | — | |
| SCHEMBL22967702 | 0.77 | — | — | |
| SCHEMBL22967940 | 0.72 | — | — | |
| SCHEMBL3436793 | 0.72 | — | — | |
| SCHEMBL26787103 | 0.72 | — | — | |
| SCHEMBL26787101 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL31378819 | 0.72 | PIK3CD (0.32) | — | |
| SCHEMBL20160908 | 0.71 | PIK3CD (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128824-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUND | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2023-04-27 | — | — | US | disclosed |
| US-20230128824-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUND | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2023-04-27 | — | — | US | disclosed |
| EP-4130000-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUND | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2023-02-08 | — | — | EP | disclosed |