Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255066 | 0.82 | DYRK1A (0.47) | DYRK1ANAMPTKDM4EALDH1A1KMT2A | |
| SCHEMBL24087053 | 0.75 | DYRK1A (0.52) | DYRK1ANAMPTKDM4EALDH1A1 | |
| SCHEMBL18306988 | 0.71 | DYRK1A (0.52) | DYRK1ANAMPTKDM4EALDH1A1 | |
| SCHEMBL9611694 | 0.71 | DYRK1A (0.52) | DYRK1ANAMPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL18371401 | 0.71 | DYRK1A (0.52) | DYRK1ANAMPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL484140 | 0.71 | DYRK1A (0.52) | DYRK1ANAMPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL19053825 | 0.71 | DYRK1A (0.52) | DYRK1ANAMPTKDM4EALDH1A1RAB9A | |
| SCHEMBL3034110 | 0.71 | MCHR1 (0.56) | DYRK1AGRM5NAMPTCYP1A2METAP2 | |
| SCHEMBL15639366 | 0.70 | MAOB (0.44) | DYRK1AGRM5NAMPTKDM4EALDH1A1 | |
| Bromide SCHEMBL4315989 | 0.69 | DYRK1A (0.50) | DYRK1ANAMPTKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230037538-A1 | ANTI-ALS COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230037538-A1 | ANTI-ALS COMPOUNDS | TARDBP, GRN, NLN | DYRK1A 4795/4885GRM5 643/4885NAMPT 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.