SCHEMBL24997805

SCHEMBL24997805

CCCCCc1cc(CC)c(C/C=C(\C)CCC=C(C)C)c(OC)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 6/20 0.64
TRPV1 Q8NER1 4/20 0.64
CNR1 P21554 2/20 0.64
CNR2 P34972 2/20 0.64
SLC6A3 Q01959 2/20 0.64
TRPA1 O75762 1/20 0.64
INHA P05111 1/20 0.64
SLC6A2 P23975 1/20 0.64
HTR2A P28223 1/20 0.64
SLC6A4 P31645 1/20 0.64
OPRM1 P35372 1/20 0.64
KCNH2 Q12809 1/20 0.64
TRPM8 Q7Z2W7 1/20 0.64
TRPV3 Q8NET8 1/20 0.64
TRPV4 Q9HBA0 1/20 0.64
TRPV2 Q9Y5S1 1/20 0.64
TRPM7 Q96QT4 1/20 0.52
DAGLA Q9Y4D2 1/20 0.52
PPARA Q07869 3/20 0.50
PPARD Q03181 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21864132 0.92 PPARG (0.71) PPARGTRPV1CNR1CNR2SLC6A3
SCHEMBL25341432 0.92 PPARG (0.71) PPARGTRPV1CNR1CNR2SLC6A3
SCHEMBL25342653 0.91 PPARG (0.70) PPARGTRPV1CNR1CNR2SLC6A3
SCHEMBL25342650 0.91 PPARG (0.70) PPARGTRPV1CNR1CNR2SLC6A3
SCHEMBL13214110 0.88 PPARG (0.80) PPARGTRPV1CNR1CNR2SLC6A3
SCHEMBL29855454 0.88 PPARG (0.80) PPARGTRPV1CNR1CNR2SLC6A3
SCHEMBL25341797 0.88 PPARG (0.80) PPARGTRPV1CNR1CNR2SLC6A3
SCHEMBL25341069 0.87 PPARG (0.78) PPARGTRPV1CNR1CNR2SLC6A3
SCHEMBL25341073 0.87 PPARG (0.78) PPARGTRPV1CNR1CNR2SLC6A3
SCHEMBL24556014 0.86 PPARG (0.60) PPARGTRPV1CNR1CNR2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023015253-A1 CANNABINOID DERIVATIVES AND THEIR USE DEMEETRA AGBIO, INC. (US) 2023-02-09 WO disclosed