SCHEMBL25001077 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	LPAR1	Q92633	8/20	0.53

▸	ALDH1A1	P00352	3/20	0.52

▸	TP53	P04637	1/20	0.41

▸	HTT	P42858	1/20	0.41

▸	LMNA	P02545	3/20	0.40

▸	AKR1C1	Q04828	1/20	0.40

▸	TSHR	P16473	2/20	0.40

▸	NPSR1	Q6W5P4	1/20	0.40

▸	CYP2C19	P33261	2/20	0.39

▸	NPC1	O15118	1/20	0.39

▸	MAPT	P10636	1/20	0.39

▸	CYP2C9	P11712	1/20	0.39

▸	RAB9A	P51151	1/20	0.39

▸	TDP1	Q9NUW8	1/20	0.39

▸	CYP3A4	P08684	3/20	0.38

▸	SMN1; SMN2	Q16637	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25000959	0.85	LPAR1 (0.53)	LPAR1ALDH1A1TP53HTTLMNA
SCHEMBL25000939	0.83	LPAR1 (0.45)	LPAR1ALDH1A1LMNAAKR1C1CYP3A4
SCHEMBL30168410	0.83	LPAR1 (0.42)	LPAR1ALDH1A1HTTLMNAAKR1C1
SCHEMBL25001786	0.83	LPAR1 (0.42)	LPAR1ALDH1A1HTTLMNAAKR1C1
SCHEMBL30844788	0.81	LPAR1 (0.54)	LPAR1AKR1C1CYP3A4
SCHEMBL21582362	0.81	LPAR1 (0.54)	LPAR1AKR1C1CYP3A4
SCHEMBL25001523	0.78	LPAR1 (0.41)	LPAR1LMNAAKR1C1CYP3A4
SCHEMBL30168354	0.78	LPAR1 (0.41)	LPAR1LMNAAKR1C1CYP3A4
SCHEMBL21582272	0.77	LPAR1 (0.52)	LPAR1LMNAAKR1C1CYP3A4
SCHEMBL29813497	0.77	LPAR1 (0.52)	LPAR1LMNAAKR1C1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023014907-A1	LPAR1 ANTAGONISTS AND USES THEREOF	Pipeline Therapeutics, Inc. (US)	2023-02-09	—	—	WO	disclosed