Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.55 |
| ▸ | BTK | Q06187 | 1/20 | 0.55 |
| ▸ | TTK | P33981 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001534 | 0.94 | EGFR (0.56) | EGFR | |
| SCHEMBL25001947 | 0.94 | EGFR (0.54) | EGFR | |
| SCHEMBL25820802 | 0.92 | EGFR (0.58) | EGFRBTKTTK | |
| SCHEMBL25001622 | 0.92 | EGFR (0.48) | EGFRBTK | |
| SCHEMBL25001595 | 0.92 | EGFR (0.48) | EGFRBTKTTK | |
| SCHEMBL25002508 | 0.92 | EGFR (0.52) | EGFRBTK | |
| SCHEMBL25002403 | 0.92 | EGFR (0.50) | EGFRBTK | |
| SCHEMBL29877082 | 0.92 | EGFR (0.50) | EGFRBTK | |
| SCHEMBL25001527 | 0.92 | EGFR (0.55) | EGFRBTKTTK | |
| SCHEMBL23442652 | 0.92 | EGFR (0.66) | EGFRBTKTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129996-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-02-08 | — | — | EP | disclosed |