Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25002831 | 0.94 | EGFR (0.53) | EGFR | |
| SCHEMBL25002771 | 0.94 | EGFR (0.48) | EGFRLRRK2 | |
| SCHEMBL25002699 | 0.92 | EGFR (0.45) | EGFR | |
| SCHEMBL25001663 | 0.91 | EGFR (0.47) | EGFR | |
| SCHEMBL25001878 | 0.91 | EGFR (0.53) | EGFR | |
| SCHEMBL25001797 | 0.90 | EGFR (0.48) | EGFR | |
| SCHEMBL25002419 | 0.90 | EGFR (0.47) | EGFRLRRK2 | |
| SCHEMBL25001823 | 0.89 | EGFR (0.47) | EGFRLRRK2 | |
| SCHEMBL25002041 | 0.88 | EGFR (0.45) | EGFR | |
| SCHEMBL25002436 | 0.88 | EGFR (0.44) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129996-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-02-08 | — | — | EP | disclosed |