Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565532 | 0.88 | GRM2 (1.00) | GRM2GRM7 | |
| SCHEMBL565531 | 0.88 | GRM2 (1.00) | GRM2GRM7 | |
| SCHEMBL564687 | 0.83 | GRM2 (0.79) | GRM2GRM7 | |
| SCHEMBL564686 | 0.83 | GRM2 (0.79) | GRM2GRM7 | |
| SCHEMBL566125 | 0.77 | GRM2 (0.64) | GRM2GRM7 | |
| SCHEMBL19139297 | 0.74 | GRM2 (0.83) | GRM2GRM7 | |
| SCHEMBL921517 | 0.73 | GRM2 (1.00) | GRM2GRM7 | |
| SCHEMBL12907976 | 0.73 | GRM2 (1.00) | GRM2GRM7 | |
| SCHEMBL565359 | 0.72 | GRM2 (0.79) | GRM2GRM7 | |
| SCHEMBL565358 | 0.72 | GRM2 (0.79) | GRM2GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373649-A1 | INDOLE AND BENZOXAZINE DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Ortho-McNeil-Janssen Pharmaceuticals, Inc. (US) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010060589-A1 | INDOLE AND BENZOXAZINE DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC. (US) | 2010-06-03 | — | — | WO | disclosed |