Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 1.00 |
| ▸ | HDAC2 | Q92769 | 18/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 17/20 | 1.00 |
| ▸ | NCOR2 | Q9Y618 | 7/20 | 1.00 |
| ▸ | NAMPT | P43490 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180461 | 0.85 | HDAC2 (1.00) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL25003417 | 0.85 | HDAC2 (1.00) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL28961535 | 0.81 | HDAC3 (1.00) | HDAC1HDAC2HDAC3NCOR2NAMPT | |
| SCHEMBL28918520 | 0.81 | HDAC3 (1.00) | HDAC1HDAC2HDAC3NCOR2NAMPT | |
| SCHEMBL25003415 | 0.79 | HDAC3 (1.00) | HDAC1HDAC2HDAC3NCOR2NAMPT | |
| SCHEMBL28918339 | 0.78 | HDAC3 (1.00) | HDAC1HDAC2HDAC3NCOR2NAMPT | |
| SCHEMBL28970468 | 0.78 | HDAC3 (0.85) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL25003420 | 0.78 | HDAC1 (1.00) | HDAC1HDAC2HDAC3NCOR2NAMPT | |
| SCHEMBL25002622 | 0.76 | HDAC1 (1.00) | HDAC1HDAC2HDAC3NCOR2NAMPT | |
| SCHEMBL30180440 | 0.76 | HDAC1 (1.00) | HDAC1HDAC2HDAC3NCOR2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703736-A | Multi-target inhibitors targeting HDAC and NAD synthesis and uses thereof | 中国海洋大学 | 2023-02-17 | — | — | CN | claimed |
| CN-115703736-B | Multi-target inhibitor targeting HDAC and NAD synthesis and application thereof | 中国海洋大学 | 2025-05-16 | — | — | CN | disclosed |
| US-20240327418-A1 | MULTI-TARGET INHIBITOR TARGETING HDAC AND NAD SYNTHESIS AND USE OF MULTI-TARGET INHIBITOR | OCEAN UNIVERSITY OF CHINA (CN) | 2024-10-03 | — | — | US | disclosed |
| WO-2023011416-A1 | MULTI-TARGET INHIBITOR TARGETING HDAC AND NAD SYNTHESIS AND USE OF MULTI-TARGET INHIBITOR | 中国海洋大学 | 2023-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327418-A1 | MULTI-TARGET INHIBITOR TARGETING HDAC AND NAD SYNTHESIS AND USE OF MULTI-TARGET INHIBITOR | HDAC3, HDAC1, HDAC11 | HDAC1 2/4885HDAC2 4/4885HDAC3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.