Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29280753 | 0.87 | MAPT (0.45) | MAPTLMNAL3MBTL1TDP1GAA | |
| SCHEMBL1625301 | 0.86 | MAPT (0.46) | MAPTLMNAL3MBTL1TDP1GAA | |
| SCHEMBL25004693 | 0.86 | MAPT (0.46) | MAPTLMNAL3MBTL1TDP1GAA | |
| SCHEMBL31026401 | 0.86 | MAPT (0.45) | MAPTLMNAL3MBTL1TDP1GAA | |
| Hydrochloric Acid SCHEMBL23089681 | 0.85 | MAPT (0.45) | MAPTLMNAL3MBTL1TDP1GAA | |
| SCHEMBL25004233 | 0.81 | IGF1R (0.51) | MAPTLMNAL3MBTL1TDP1GAA | |
| SCHEMBL30810306 | 0.81 | IGF1R (0.51) | MAPTLMNAL3MBTL1TDP1GAA | |
| SCHEMBL29280741 | 0.79 | MAPT (0.42) | MAPTLMNAL3MBTL1TDP1GAA | |
| Hydrochloric Acid SCHEMBL1999863 | 0.78 | MAPT (0.42) | MAPTLMNAL3MBTL1TDP1GAA | |
| SCHEMBL30225088 | 0.78 | PTGER4 (0.56) | MAPTLMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023012820-A1 | A PROCESS FOR THE PREPARATION OF GRAPIPRANT AND ITS INTERMEDIATES | ZENFOLD SUSTAINABLE TECHNOLOGIES PRIVATE LIMITED (IN) | 2023-02-09 | — | — | WO | disclosed |