Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 12/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17237650 | 1.00 | F9 (0.57) | F9TP53ITGB3ITGA2BHDAC6 | |
| SCHEMBL1945578 | 0.90 | F9 (0.54) | F9HDAC6MAPT | |
| SCHEMBL1945581 | 0.90 | F9 (0.54) | F9HDAC6MAPT | |
| SCHEMBL1947266 | 0.89 | F9 (0.73) | F9ITGB3ITGA2B | |
| SCHEMBL12545875 | 0.89 | F9 (0.57) | F9HDAC6MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL1947337 | 0.89 | F9 (0.72) | F9ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL1947626 | 0.86 | F9 (0.49) | F9ITGB3HDAC6 | |
| SCHEMBL12569571 | 0.86 | F9 (0.54) | F9HDAC6 | |
| SCHEMBL17237624 | 0.86 | F9 (0.57) | F9 | |
| SCHEMBL12546788 | 0.84 | F9 (0.53) | F9HDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373634-B1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARM CO LTD (JP) | 2015-11-11 | — | — | EP | claimed |
| EP-2373634-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | Mochida Pharmaceutical Co., Ltd. (JP) | 2011-10-12 | — | — | EP | claimed |
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | claimed |