Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 10/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.39 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31147662 | 1.00 | MAPK3 (0.42) | MAPK3ALKFSCN1SYKMET | |
| SCHEMBL27238029 | 0.91 | MAPK3 (0.42) | MAPK3ALKFSCN1SYK | |
| SCHEMBL31147650 | 0.84 | MAPK3 (0.51) | MAPK3ALKSYKMET | |
| SCHEMBL25004484 | 0.84 | MAPK3 (0.51) | MAPK3ALKSYKMET | |
| SCHEMBL27238021 | 0.81 | TYK2 (0.46) | MAPK3ALKMETLRRK2 | |
| SCHEMBL31147667 | 0.81 | TYK2 (0.46) | MAPK3ALKMETLRRK2 | |
| SCHEMBL25004482 | 0.80 | MAPK3 (0.53) | MAPK3ALKMET | |
| SCHEMBL31147612 | 0.80 | MAPK3 (0.53) | MAPK3ALKMET | |
| SCHEMBL25005171 | 0.79 | ALK (0.39) | MAPK3ALKLRRK2 | |
| SCHEMBL31147670 | 0.77 | CCNA2 (0.41) | MAPK3ALKLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023014022-A1 | PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2023-02-09 | — | — | WO | disclosed |