Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.59 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.59 |
| ▸ | EML4 | Q9HC35 | 3/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.58 |
| ▸ | INSR | P06213 | 1/20 | 0.58 |
| ▸ | ROS1 | P08922 | 1/20 | 0.58 |
| ▸ | FER | P16591 | 1/20 | 0.58 |
| ▸ | LTK | P29376 | 1/20 | 0.58 |
| ▸ | BLK | P51451 | 1/20 | 0.58 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.58 |
| ▸ | BTK | Q06187 | 1/20 | 0.58 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.58 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.58 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30223009 | 1.00 | EGFR (0.59) | EGFRALKEML4ERBB2INSR | |
| SCHEMBL25004682 | 0.99 | EGFR (0.60) | EGFRALKEML4ERBB2INSR | |
| SCHEMBL30222930 | 0.99 | EGFR (0.60) | EGFRALKEML4ERBB2INSR | |
| SCHEMBL25005401 | 0.98 | EGFR (0.60) | EGFRALKEML4ERBB2INSR | |
| SCHEMBL30222883 | 0.96 | EGFR (0.62) | EGFRALKEML4ERBB2INSR | |
| SCHEMBL25004683 | 0.96 | EGFR (0.62) | EGFRALKEML4ERBB2INSR | |
| SCHEMBL30223103 | 0.94 | EGFR (0.62) | EGFRALKEML4ERBB2INSR | |
| SCHEMBL25005691 | 0.94 | EGFR (0.59) | EGFRALKEML4ERBB2INSR | |
| SCHEMBL30222967 | 0.94 | EGFR (0.59) | EGFRALKEML4ERBB2INSR | |
| SCHEMBL25004676 | 0.93 | EGFR (0.59) | EGFRALKEML4ERBB2INSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4382514-A1 | PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2024-06-12 | — | — | EP | claimed |
| EP-4382514-A1 | PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2024-06-12 | — | — | EP | disclosed |
| WO-2023014022-A1 | PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2023-02-09 | — | — | WO | disclosed |