Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25004772 | 0.84 | TLR2 (0.53) | MAOAKMT2AALDH1A1HPGDTLR2 | |
| SCHEMBL23995338 | 0.83 | KMT2A (0.54) | KMT2AALDH1A1MEN1SMN1; SMN2LMNA | |
| SCHEMBL23992985 | 0.83 | TLR2 (0.52) | MAOAALDH1A1TLR2TLR1 | |
| SCHEMBL23995257 | 0.83 | TLR2 (0.46) | MAOAKMT2AMEN1LMNATLR2 | |
| SCHEMBL23992982 | 0.83 | TLR2 (0.46) | MAOAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL25005523 | 0.83 | TLR2 (0.52) | MAOAALDH1A1TLR2TLR1 | |
| SCHEMBL25004777 | 0.82 | KDM1A (0.48) | MAOAKMT2AMEN1HPGDTLR2 | |
| SCHEMBL25004771 | 0.82 | TLR2 (0.44) | MAOAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL25004781 | 0.82 | TLR2 (0.46) | MAOAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL25004983 | 0.81 | NAMPT (0.49) | MAOAHPGDTLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | MAOA 1171/4885KMT2A 2253/4885ALDH1A1 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.