Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.55 |
| ▸ | BTK | Q06187 | 4/20 | 0.55 |
| ▸ | JAK3 | P52333 | 3/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.53 |
| ▸ | INSR | P06213 | 1/20 | 0.52 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30223076 | 1.00 | EGFR (0.55) | EGFRBTKJAK3ALKINSR | |
| SCHEMBL30222988 | 0.94 | EGFR (0.59) | EGFRBTKJAK3ALKINSR | |
| SCHEMBL25005402 | 0.94 | EGFR (0.59) | EGFRBTKJAK3ALKINSR | |
| SCHEMBL30223055 | 0.94 | EGFR (0.59) | EGFRBTKJAK3ALKINSR | |
| SCHEMBL25005400 | 0.94 | EGFR (0.59) | EGFRBTKJAK3ALKINSR | |
| SCHEMBL30223103 | 0.89 | EGFR (0.62) | EGFRBTKALKINSR | |
| SCHEMBL30223175 | 0.89 | EGFR (0.57) | EGFRBTKALKINSRMAPK3 | |
| SCHEMBL23255650 | 0.87 | EGFR (0.64) | EGFRBTKJAK3MAPK3 | |
| SCHEMBL30223004 | 0.86 | EGFR (0.61) | EGFRBTKALKINSR | |
| SCHEMBL25004682 | 0.84 | EGFR (0.60) | EGFRBTKALKINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023014022-A1 | PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2023-02-09 | — | — | WO | disclosed |