Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498738 | 0.83 | PARP1 (0.34) | PARP1 | |
| Trifluoroacetic Acid SCHEMBL2500718 | 0.80 | GRIN2D (0.41) | PARP1 | |
| SCHEMBL2495511 | 0.80 | CDK2 (0.33) | PARP1HPGD | |
| SCHEMBL2500031 | 0.76 | GRIN2D (0.47) | PARP1 | |
| Acetic Acid SCHEMBL2498732 | 0.72 | GRIN2D (0.44) | PARP1 | |
| SCHEMBL2496167 | 0.69 | CYP4F2 (0.33) | PARP1HPGD | |
| SCHEMBL2501354 | 0.69 | PARP1 (0.40) | PARP1 | |
| SCHEMBL7346990 | 0.69 | PARP1 (0.43) | PARP1 | |
| SCHEMBL27457721 | 0.69 | PARP1 (0.40) | PARP1HPGD | |
| SCHEMBL14755023 | 0.69 | KCNJ5 (0.47) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373628-A1 | NOVEL COMPOUNDS | Glaxo Group Limited (GB) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010070021-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-06-24 | — | — | WO | disclosed |