Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 20/20 | 0.84 |
| ▸ | CDC7 | O00311 | 3/20 | 0.80 |
| ▸ | PLK4 | O00444 | 3/20 | 0.80 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.80 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.80 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.80 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.80 |
| ▸ | PRKCG | P05129 | 3/20 | 0.80 |
| ▸ | CDK1 | P06493 | 3/20 | 0.80 |
| ▸ | PRKACA | P17612 | 3/20 | 0.80 |
| ▸ | CDK2 | P24941 | 3/20 | 0.80 |
| ▸ | MARK3 | P27448 | 3/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.80 |
| ▸ | FRK | P42685 | 3/20 | 0.80 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.80 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.80 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.80 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.80 |
| ▸ | GSK3A | P49840 | 3/20 | 0.80 |
| ▸ | GSK3B | P49841 | 3/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185849 | 0.92 | JAK2 (1.00) | JAK2CDC7PLK4MAPK13DAPK3 | |
| SCHEMBL1133999 | 0.89 | JAK2 (1.00) | JAK2CDC7PLK4MAPK13DAPK3 | |
| SCHEMBL1208545 | 0.87 | JAK2 (1.00) | JAK2CDC7PLK4MAPK13DAPK3 | |
| SCHEMBL1207133 | 0.87 | JAK2 (0.75) | JAK2CDC7PLK4MAPK13DAPK3 | |
| SCHEMBL13732436 | 0.87 | JAK2 (1.00) | JAK2CDC7PLK4MAPK13DAPK3 | |
| SCHEMBL4187423 | 0.87 | JAK2 (0.76) | JAK2CDC7PLK4MAPK13DAPK3 | |
| Hydrochloric Acid SCHEMBL1208297 | 0.86 | JAK2 (0.74) | JAK2CDC7PLK4MAPK13DAPK3 | |
| Hydrochloric Acid SCHEMBL1133736 | 0.86 | JAK2 (0.98) | JAK2CDC7PLK4MAPK13DAPK3 | |
| SCHEMBL13731118 | 0.86 | JAK2 (0.82) | JAK2CDC7PLK4MAPK13DAPK3 | |
| SCHEMBL4179135 | 0.86 | JAK2 (0.86) | JAK2CDC7PLK4MAPK13DAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129293-A1 | NERVE CELL DEGENERATION INHIBITOR | Kyoto University (JP) | 2023-02-08 | — | — | EP | disclosed |