Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 2/20 | 0.59 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL372599 | 0.83 | HPGD (0.51) | SSTR3SCN9ASMN1; SMN2KDM1AMAOA | |
| SCHEMBL5384594 | 0.83 | HPGD (0.51) | SSTR3SCN9ASMN1; SMN2KDM1AMAOA | |
| SCHEMBL5394785 | 0.83 | HPGD (0.51) | SSTR3SCN9ASMN1; SMN2KDM1AMAOA | |
| SCHEMBL3044112 | 0.82 | S1PR5 (0.53) | — | |
| SCHEMBL4480119 | 0.82 | SSTR3 (0.63) | SSTR3SCN9AKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL8313950 | 0.81 | SSTR3 (0.64) | SSTR3KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL22105522 | 0.80 | SSTR3 (0.54) | SSTR3SCN9ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL3037877 | 0.78 | S1PR5 (0.52) | SSTR3 | |
| SCHEMBL26129575 | 0.77 | SSTR3 (0.57) | SSTR3SMN1; SMN2NPC1RAB9AKDM1A | |
| SCHEMBL26126666 | 0.77 | SSTR3 (0.57) | SSTR3SMN1; SMN2NPC1RAB9AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030489-B2 | Ornithine derivative | ASTELLAS PHARMA INC. (JP) | 2011-10-04 | — | — | US | disclosed |