Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 11/20 | 0.43 |
| ▸ | TTK | P33981 | 6/20 | 0.41 |
| ▸ | LCK | P06239 | 4/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123030 | 0.88 | PTK6 (0.47) | PTK6TTKLCKAURKBNR3C1 | |
| Hydrochloric Acid SCHEMBL30171859 | 0.88 | PTK6 (0.47) | PTK6TTKLCKAURKBNR3C1 | |
| SCHEMBL25013246 | 0.87 | TTK (0.48) | PTK6TTKAURKB | |
| SCHEMBL22122995 | 0.84 | TTK (0.46) | PTK6TTKLCKAURKB | |
| SCHEMBL22123765 | 0.82 | TTK (0.46) | PTK6TTKLCKAURKB | |
| SCHEMBL22123675 | 0.82 | TTK (0.46) | PTK6TTKLCKAURKB | |
| SCHEMBL22139088 | 0.82 | TTK (0.44) | PTK6TTKLCKAURKB | |
| Hydrochloric Acid SCHEMBL25167713 | 0.81 | TTK (0.45) | PTK6TTKLCKAURKB | |
| SCHEMBL22123694 | 0.81 | TTK (0.41) | PTK6TTKLCKAURKBPTK2 | |
| SCHEMBL30172065 | 0.81 | TTK (0.41) | PTK6TTKLCKAURKBPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |