Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 15/20 | 0.40 |
| ▸ | MAPKAPK5 | Q8IW41 | 3/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30171886 | 0.92 | TTK (0.45) | TTKMAPKAPK5PTK6 | |
| SCHEMBL24870806 | 0.92 | TTK (0.45) | TTKMAPKAPK5PTK6 | |
| SCHEMBL22123002 | 0.86 | TTK (0.45) | TTKMAPKAPK5PTK6 | |
| SCHEMBL22123975 | 0.85 | PTK6 (0.45) | TTKMAPKAPK5PTK6 | |
| Hydrochloric Acid SCHEMBL25176493 | 0.85 | TTK (0.45) | TTKMAPKAPK5PTK6 | |
| SCHEMBL22124269 | 0.84 | PTK6 (0.42) | TTKMAPKAPK5PTK6 | |
| SCHEMBL22124272 | 0.84 | PTK6 (0.42) | TTKMAPKAPK5PTK6 | |
| SCHEMBL30177715 | 0.84 | TTK (0.49) | TTKMAPKAPK5PTK6SYK | |
| SCHEMBL24112551 | 0.83 | TTK (0.44) | TTKMAPKAPK5PTK6 | |
| SCHEMBL22123451 | 0.83 | TTK (0.48) | TTKMAPKAPK5PTK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |