Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 17/20 | 0.49 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.40 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123439 | 0.89 | TTK (0.49) | TTKPTK6MAPKAPK5 | |
| SCHEMBL22123438 | 0.89 | TTK (0.49) | TTKPTK6MAPKAPK5 | |
| SCHEMBL22124793 | 0.89 | TTK (0.49) | TTKPTK6MAPKAPK5 | |
| SCHEMBL24870824 | 0.86 | TTK (0.45) | TTKPTK6MAPKAPK5 | |
| SCHEMBL25013028 | 0.84 | TTK (0.43) | TTKPTK6MAPKAPK5 | |
| SCHEMBL25013062 | 0.81 | TTK (0.40) | TTKPTK6MAPKAPK5 | |
| SCHEMBL25013701 | 0.81 | TTK (0.50) | TTKPTK6MAPKAPK5 | |
| SCHEMBL22124068 | 0.80 | PTK6 (0.46) | TTKPTK6MAPKAPK5 | |
| SCHEMBL22124420 | 0.80 | PTK6 (0.46) | TTKPTK6MAPKAPK5 | |
| SCHEMBL22124070 | 0.80 | PTK6 (0.46) | TTKPTK6MAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |