⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylsulfanylmethane SCHEMBL6940181 | 1.00 | — | — | |
| Methylsulfanylmethane SCHEMBL23701635 | 1.00 | — | — | |
| Methylsulfanylmethane SCHEMBL4498934 | 1.00 | TSHR (0.43) | — | |
| Methylsulfanylmethane SCHEMBL9413612 | 0.91 | — | — | |
| Methylsulfanylmethane SCHEMBL27928784 | 0.89 | — | — | |
| Methylsulfanylmethane SCHEMBL1618 | 0.89 | — | — | |
| Methylsulfanylmethane SCHEMBL5440614 | 0.89 | — | — | |
| Methylsulfanylmethane SCHEMBL1330443 | 0.89 | — | — | |
| Methylsulfanylmethane SCHEMBL5139388 | 0.80 | — | — | |
| Methylsulfanylmethane SCHEMBL7706316 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458976-B | Pyrrolidine GPR40 modulators for the treatment of diseases such as diabetes | 百时美施贵宝公司 | 2020-05-22 | — | — | CN | disclosed |
| CN-104812748-B | Pyrazoline GPR40 conditioning agents | 百时美施贵宝公司 | 2017-10-24 | — | — | CN | disclosed |
| CN-104918935-B | dihydropyrazole GPR40 modulators | 百时美施贵宝公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-105121426-B | Pyrrolidine GPR40 regulators | 百时美施贵宝公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-106458976-A | Pyrrolidine gpr40 modulators for the treatment of diseases such as diabetes | 百时美施贵宝公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106458987-A | Pyrrolidine GPR40 modulators for the treatment of diseases such as diabetes | 百时美施贵宝公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105121426-A | Pyrrolidine GPR40 modulators | BRISTOL MYERS SQUIBB CO | 2015-12-02 | — | — | CN | disclosed |
| CN-102066323-B | Novel estrogen receptor ligands | KAROBIO AB | 2015-05-13 | — | — | CN | disclosed |
| US-8030499-B2 | 1,3-dihydro-2H-indole-2-one compound and pyrrolidine-2-one compound fused with aromatic heterocycle | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-10-04 | — | — | US | disclosed |
| CN-102066323-A | Novel estrogen receptor ligands | KAROBIO AB | 2011-05-18 | — | — | CN | disclosed |
| US-20070112059-A1 | CYANOPYRROLIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. | 2007-05-17 | — | — | US | disclosed |
| EP-1746086-A1 | Cyanopyrrolidine derivatives | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2007-01-24 | — | — | EP | disclosed |
| US-20060276449-A1 | 1,3-Dihydro-2h-indol-2-one derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1659121-A1 | 1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-05-24 | — | — | EP | disclosed |
| US-20040072892-A1 | Cyanopyrrolidine derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1333025-A1 | CYANOPYRROLIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-0601909-B1 | Dibekacin derivatives and arbekacin derivatives active against resistant bacteria, and the production thereof | ZAIDAN HOJIN BISEIBUTSU (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5618795-A | Dibekacin derivatives and arbekacin derivatives active against resistant bacteria, and the production thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1997-04-08 | — | — | US | disclosed |
| US-5488038-A | Dibekacin derivatives and arbekacin derivatives active against resistant bacteria | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1996-01-30 | — | — | US | disclosed |
| EP-0601909-A2 | Dibekacin derivatives and arbekacin derivatives active against resistant bacteria, and the production thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1994-06-15 | — | — | EP | disclosed |