Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20974882 | 0.92 | KRAS (0.66) | KRAS | |
| SCHEMBL19948821 | 0.92 | KRAS (0.66) | KRAS | |
| SCHEMBL30188614 | 0.92 | KRAS (0.66) | KRAS | |
| SCHEMBL30302293 | 0.92 | KRAS (0.66) | KRAS | |
| SCHEMBL28489112 | 0.92 | KRAS (0.66) | KRAS | |
| SCHEMBL31089743 | 0.87 | KRAS (0.74) | KRAS | |
| Trifluoroacetic Acid SCHEMBL31185654 | 0.87 | KRAS (0.63) | KRAS | |
| Trifluoroacetic Acid SCHEMBL28589217 | 0.87 | KRAS (0.63) | KRAS | |
| SCHEMBL25323802 | 0.87 | KRAS (0.73) | KRAS | |
| SCHEMBL24622930 | 0.87 | KRAS (0.73) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710439-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-02-15 | — | — | EP | disclosed |