Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21846309 | 0.92 | KRAS (0.47) | KRASSOS1 | |
| SCHEMBL22994683 | 0.88 | KRAS (0.46) | KRASSOS1 | |
| SCHEMBL21846319 | 0.88 | KRAS (0.46) | KRASSOS1 | |
| SCHEMBL21846316 | 0.85 | KRAS (0.62) | KRASSOS1 | |
| SCHEMBL25021723 | 0.85 | KRAS (0.62) | KRASSOS1 | |
| SCHEMBL21912203 | 0.84 | KRAS (0.43) | KRASSOS1 | |
| SCHEMBL21734112 | 0.81 | KRAS (0.55) | KRASSOS1 | |
| SCHEMBL25020959 | 0.81 | KRAS (0.44) | KRASSOS1 | |
| SCHEMBL23645670 | 0.78 | KRAS (0.45) | KRASSOS1 | |
| SCHEMBL23841437 | 0.77 | KRAS (0.56) | KRASSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710439-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-02-15 | — | — | EP | disclosed |